The 307 Sample Oxidizer is an automatic preparation and oxidization system for both single and dual radiolabeled samples containing 3H and/or 14C for use in liquid scintillation counting. The 307 Sample Oxidizer ensures reliable combustion of biological, environmental and industrial samples. This system includes the following standard features and benefits: 

• Single “push button” operation initiates automatic cycle, positioning of vials and ignition basket, non-catalytic combustion, dispensing of scintillation cocktails and carbon dioxide trapping agent, and system cleaning. 

• Physical separation of 3H and 14C radionuclides from dual labeled sample material for ease of sample analysis.

• Minimizes optical and chemical quenching. Reduces chemiluminescence in most sample preparations, increases statistical accuracy of liquid scintillation counting results. Eliminates self-absorption.

• Observation of combustion allows for visual inspection during sample burn.

• Complete combustion of liquid, wet or dry sample eliminates the need for chemical solubilization.

• Ensures maximum radionuclide recovery for 14C with sample size equivalent up to 40 millimoles of carbon dioxide and up to 85 millimoles of water for samples containing 3H (up to 1.5 grams). 

• Radionuclide recovery for both 3H and 14C of >97% maximizes radionuclide separation for single label analysis using liquid scintillation counting techniques and an efficiency quench correlation curve for each radionuclide.

• Radionuclide memory of less than 0.08% for most 3H and 14C labeled sample materials. 

• Non-catalytic combustion eliminates catalyst usage, cost and replacement. • Accommodates 20 mL glass or low cost polyethylene vials. 

• Capacity to process up to 60 samples per hour for each radionuclide. 

• Unique design bellows-type reagent metering pumps. Pumps adjustable from 0 to 18 milliliters, automatically dispense accurate volumes of both 3H and 14C scintillation cocktails and carbon dioxide trapping agent.

• Long life, removable platinum ignition basket. 

• Non-pressurized reagent storage tank capacity of five liters for each reagent allows up to 500 sample combustions between refills.

• Ambient temperature trapping of water and carbon dioxide provides safe and clean operation. 

• Accessory kit with spare parts; included are additional O-rings, glass combustion flask, wrench, seals, and assorted small parts.

The 307 Sample Oxidizer provides a simple, automatic method of preparation for samples that are otherwise difficult to prepare for liquid scintillation counting. The instrument combusts the sample material in an oxygen-enriched atmosphere with a continuous flow of oxygen to constituent water vapor and carbon dioxide using a patented process to achieve physical separation of 3H and 14C radionuclides into two separate counting vials.

• Sample material is placed into a Combusto-ConeTM and may be either dry, wet or liquid. The Combusto-Cone with sample is placed into the platinum ignition basket.

• For single labeled 14C samples or dual labeled 3H/14C samples, the system will accommodate a sample size equivalent up to 40 millimoles of CO2 (approximately 1.2 g of filter paper) and will meet all performance specifications.

• For 3H samples, the system will accommodate a sample size equivalent of up to 85 millimoles of H2O (approximately 1.5 mL of water). Larger 3H samples may be handled by burning multiple samples and trapping the water vapor in the same counting vial. 

• System includes a combustion timer for setting combustion time from 0 to 5 minutes. Up to 60 samples per hour of each nuclide can be prepared. 

• Combustion flask enclosure is heated to approximately 125°C to avoid condensation of 3H2O vapor. 

• A double safety window is provided for visual inspection of sample combustion.

• The combustion flask compartment door is interlocked so that the automatic cycle cannot be initiated if the door is open.

• The combustion flask and ignition basket are easily removed for cleaning.